Study Confirms CDI 500 System ‘Significantly Improves Blood Gas Management’

Ann Arbor, Michigan — December 09, 2010 — A recent clinical study favored the use of the CDI™ 500 Blood Parameter Monitoring System. "Improving Cardiopulmonary Bypass: Does Continuous Blood Gas Monitoring Have a Role to Play?” appeared in the September 2010 issue of the Journal of ExtraCorporeal Technology (JECT). Jane Ottens, CCP, Ashford Hospital, Ashford, South Australia, Australia, led the study. JECT is an international peer-reviewed periodical focused on the field of perfusion.


About the Study

In a randomized trial, the study investigated the role of in-line blood gas monitoring in the improvement of blood gas management during cardiopulmonary bypass utilizing continuous quality indicators.

Study highlights included:

  • There was a statistically significant difference in the percentage of cases where carbon dioxide partial pressure (pCO2) deviated from protocol between the Control group (20%) and the CDI group (2%) — carbon dioxide partial pressure control is needed for acid-base balance and autoregulation of blood flow to the brain, heart and lungs.

  • Use of the CDI 500 system led to improved blood gas management, minimizing the variation seen with intermittent sampling and producing tighter control of carbon dioxide partial pressure, oxygen partial pressure and pH.

"With intermittent sampling, perfusionists do not have access to realtime information and may be unaware of periods where blood gas levels are outside the appropriate ranges, and changes made to gas management may not correct the situation,” wrote Ms. Ottens.

As a result of this time delay with intermittent sampling, the results do not reflect the current metabolic state of the patient at the time the results are available and able to be interpreted by the perfusionist. "The realtime information provided by the CDI 500 system allows clinical decisions to be made and implemented immediately,” the authors wrote.



"Our aim was to investigate whether the use of the CDI 500 system resulted in an improvement in perfusion performance as determined by our blood gas management,” the study authors declared. "We have clearly demonstrated that continuous blood gas monitoring results in significantly improved blood gas management as determined by adherence to institutional protocols.

"It is therefore difficult to build an argument for not using such technology in the routine management of the patients to whom we are charged with their care,” Ms. Ottens wrote.


About the CDI System

The CDI™ 500 Blood Parameter Monitoring System is an in-line blood gas monitoring device that has been used in clinical practice for over a decade. It provides continuous realtime blood gas and electrolyte measurements for pO2, pCO2, pH, bicarbonate and potassium. The realtime information from this device can reduce the potential for delay in the diagnosis of reduced tissue perfusion and irreversible damage to the patient. Monitoring of patients' physiological state is an integral component of open heart surgery and the timeliness of information used for blood gas management is pertinent to improving patients' clinical outcomes.