Terumo Cardiovascular Group

Core Competencies

Biocompatible Coatings

X Coating

In 2000, we introduced our first biocompatible coating for products used in cardiopulmonary bypass. Xcoating™ is an amphiphilic, biopassive coating that reduces protein denaturation and platelet adhesion. This non-heparin coating for the perfusion circuit addresses the goal of heart teams everywhere — to achieve a tip-to-tip coated circuit and improve the biocompatibility of cardiopulmonary bypass.

Developed at Shonan Center, our world-class research and development facility in Kanagawa, Japan, Xcoating is now applied to perfusion circuit products at the point of manufacture at our facilities around the world.

Xcoating's benefits have led to its adoption in cardiac ORs around the world. It is biopassive and has no contraindications for patient size. It is indicated for heparin-sensitive patients.

Importantly for future product development, Xcoating can be applied to all device material surfaces, including polypropylene, polycarbonate, stainless steel, filter mesh and PVC.

Related Information:

For product applications: Terumo® Perfusion Circuits

For clinical applications: Optimizing Cardiac Surgery Resource